Shai Schubert
Feromics: Advancing immunotherapy through biology-driven AI
Shai Schubert is a biotechnology entrepreneur and co-founder and CEO of Feromics, a Boston-based functional immunomics platform company working at the intersection of biology and machine learning. At Feromics, Dr. Schubert leads the development of the Intelligent Design™ platform — a function-first discovery workflow that physically isolates immune cells based on directly observed behavior before any molecular data is collected.
This produces training-grade data with verified functional labels built in at the biological source level, enabling superior AI models that train faster, require fewer samples, and generate discoveries that translate.
Using its Intelligent DesignTM platform, Feromics assigns each immune cell a verified functional label and links it to its molecular profile-creating data that enables AI models to learn true biological causality, not just correlation. Feromics’ Intelligent DesignTM platform generates functionally verified immune transcriptomic datasets at single-cell resolution and uses them to train predictive AI models for discovery, diagnostics, and allogeneic donor selection. Once trained, in addition to supporting the development Feromics’ internal cancer immunotherapy pipeline, these models can be applied to standard sequencing data - including bulk RNA- seq, single-cell RNA-seq, and retrospective clinical datasets - enabling scalable, real-world deployment in three core application areas:
In drug discovery, Feromics enables functional candidate screening while revealing mechanisms of action and identifying predictive biomarkers.
In clinical development, it supports donor selection for allogeneic therapies, defines mechanisms of response and resistance and informs trial design.
In diagnostics, Feromics applies AI-driven models to predict clinical outcomes using functional biomarkers. For more information, visit feromics.com
To me, Shai is first and foremost a wonderful friend, unsparing with his time and advice. Together we helped galvanize a Boston-based progressive Israeli diaspora to support democratic norms in Israel, a humane future for Israelis and Palestinians alike, and to confront authoritarianism and discrimination, in all its forms, in the U.S. A passionate jazz guitarist, he believes that jazz is king!